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EnablaWhat determines the folding and stability of protein structures? In his fourth lecture, Dr. Ali Hassanali from the Abdus Salam International Centre for Theoretical Physics (ICTP) explores the intricate world of protein secondary structures, focusing specifically on alpha helices and beta sheets. Dr. Hassanali explains how these structures are stabilized through a variety of interactions, including hydrogen bonding and electrostatic effects, and the critical role of dihedral angles as illustrated by the Ramachandran plot.This lecture also highlights the essential contributions of cysteine in forming disulfide bonds, which enhance protein stability in challenging environments. By examining the interplay of molecular interactions, Dr. Hassanali provides insights into the architectural and functional significance of these secondary structures as well as their evolutionary adaptations.🎥 Join us for this <a href="https://mathstodon.xyz/tags/OpenAccess" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#OpenAccess</a> lecture and engage in discussions with Dr. Hassanali himself and other members of the Enabla community: <a href="https://enabla.com/pub/606/about" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://enabla.com/pub/606/about</a> <a href="https://mathstodon.xyz/tags/Biophysics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Biophysics</a> <a href="https://mathstodon.xyz/tags/Proteins" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Proteins</a> <a href="https://mathstodon.xyz/tags/MolecularBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MolecularBiology</a> <a href="https://mathstodon.xyz/tags/StructuralBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#StructuralBiology</a> <a href="https://mathstodon.xyz/tags/OpenScience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#OpenScience</a>

John Vaccaro (johniac)SciTech Chronicles. . . . . . . . .Mar 16th, 2025<a href="https://bit.ly/stc031625" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://bit.ly/stc031625</a><a href="https://mastodon.social/tags/dyes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#dyes</a> <a href="https://mastodon.social/tags/proteins" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#proteins</a> <a href="https://mastodon.social/tags/perylene" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#perylene</a>-bisimide <a href="https://mastodon.social/tags/supramolecular" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#supramolecular</a> <a href="https://mastodon.social/tags/brown" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#brown</a> <a href="https://mastodon.social/tags/dwarf" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#dwarf</a> <a href="https://mastodon.social/tags/Orion" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Orion</a> <a href="https://mastodon.social/tags/boundaries" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#boundaries</a> <a href="https://mastodon.social/tags/bore" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#bore</a>-fields <a href="https://mastodon.social/tags/groundwater" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#groundwater</a> <a href="https://mastodon.social/tags/infiltration" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#infiltration</a> <a href="https://mastodon.social/tags/modelling" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#modelling</a> <a href="https://mastodon.social/tags/AMR" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#AMR</a> <a href="https://mastodon.social/tags/medicine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#medicine</a> <a href="https://mastodon.social/tags/agriculture" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#agriculture</a> <a href="https://mastodon.social/tags/cf" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#cf</a>-PICIs galactic <a href="https://mastodon.social/tags/rotation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#rotation</a> <a href="https://mastodon.social/tags/Schwarzchild" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Schwarzchild</a> <a href="https://mastodon.social/tags/bounce" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#bounce</a>

Science Updates“I think it will be a gamechanger very broadly, not just for people in my field,” said senior study author James Liu, a group leader at Howard Hughes Medical Institute's Janelia Research Campus. “It was a tool developed to answer a very obscure question, but I think all biologists can use the technique in their favorite samples.”<a href="https://mastodon.social/tags/research" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#research</a> <a href="https://mastodon.social/tags/science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#science</a> <a href="https://mastodon.social/tags/biotechnology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#biotechnology</a> <a href="https://mastodon.social/tags/technology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#technology</a> <a href="https://mastodon.social/tags/RNA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#RNA</a> <a href="https://mastodon.social/tags/proteins" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#proteins</a> <a href="https://www.labroots.com/trending/clinical-and-molecular-dx/28687/cutting-edge-tech-id-rna-protein-deep-tissues" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.labroots.com/trending/clinical-and-molecular-dx/28687/cutting-edge-tech-id-rna-protein-deep-tissues</a>

Paul Houle🌀 Protein design: Flexible components allow new architectures<a href="https://phys.org/news/2025-02-protein-flexible-components-architectures.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://phys.org/news/2025-02-protein-flexible-components-architectures.html</a><a href="https://mastodon.social/tags/biotech" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#biotech</a> <a href="https://mastodon.social/tags/proteins" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#proteins</a> <a href="https://mastodon.social/tags/molbio" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#molbio</a> <a href="https://mastodon.social/tags/synthetic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#synthetic</a> <a href="https://mastodon.social/tags/biology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#biology</a> <a href="https://mastodon.social/tags/research" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#research</a>

The Conversation U.S."Pac-Man with a ponytail" <a href="https://newsie.social/tags/proteins" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#proteins</a>, as <a href="https://newsie.social/tags/GRK" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GRK</a> proteins are nicknamed, regulate everything from night vision to heartbeats. A structural biology scholar explains how studying their structure could enhance a range of drugs. <a href="https://theconversation.com/pac-man-with-a-ponytail-proteins-regulate-everything-from-night-vision-to-heartbeats-studying-what-grks-look-like-could-improve-an-array-of-drugs-248298" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://theconversation.com/pac-man-with-a-ponytail-proteins-regulate-everything-from-night-vision-to-heartbeats-studying-what-grks-look-like-could-improve-an-array-of-drugs-248298</a> Priyanka Naik, Purdue University

Fabrizio BenedettiProtein discovered that can help to fight cellular aging <a href="https://www.earth.com/news/scientists-discover-a-protein-that-reverses-cellular-aging/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.earth.com/news/scientists-discover-a-protein-that-reverses-cellular-aging/</a> <a href="https://mstdn.science/tags/aging" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#aging</a> <a href="https://mstdn.science/tags/health" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#health</a> <a href="https://mstdn.science/tags/proteins" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#proteins</a> <a href="https://mstdn.science/tags/biology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#biology</a>

michael6-Mar-2025 A new algorithm sheds light on ‘disordered’ <a href="https://mastodon.social/tags/proteins" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#proteins</a>The <a href="https://mastodon.social/tags/IntrinsicallyDisorderedProteins" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#IntrinsicallyDisorderedProteins</a> (IDPs) do not attain a stable secondary or tertiary structure and rapidly change their conformation, making <a href="https://mastodon.social/tags/structurePrediction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#structurePrediction</a> particularly challenging. These proteins although exhibit chaotic and ‘disordered’ structures, they still perform essential functions. <a href="https://www.eurekalert.org/news-releases/1075837" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.eurekalert.org/news-releases/1075837</a> <a href="https://mastodon.social/tags/science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#science</a>

CellBioNewsA gentler and more efficient method to purify <a href="https://scientificnetwork.de/tags/proteins" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#proteins</a> with light.<a href="https://scientificnetwork.de/tags/azo" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#azo</a>-benzene <a href="https://scientificnetwork.de/tags/Azo" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Azo</a>-tag <a href="https://scientificnetwork.de/tags/UV_light" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#UV_light</a> <a href="https://phys.org/news/2025-03-gentler-efficient-method-purify-proteins.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://phys.org/news/2025-03-gentler-efficient-method-purify-proteins.html</a>

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