Avatar: Aang is Jerry, Katara Elaine, Sokka George, and Toph Kramer
Harry Potter: Harry is Jerry, Hermione George, Ron Elaine and I would argue that Kramer is the Wizarding World itself
Homestuck: John is Jerry, Rose Elaine. You might think that Dave is Kramer (wacky, impulsive, different upbringing & reference points). You would be wrong. Jade is Kramer. Dave is George.
This shitpost brought to you by the Clickhole article about Seinfeld as monomyth http://www.clickhole.com/article/4-ancient-civilizations-independently-developed-ru-6873
@DialMforMara When someone says "monomyth" first you gotta ask "Whose?"